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[在大鼠中,脑桥背外侧部分兴奋时对延髓网状脊髓神经元的抑制作用,阻断运动和肌肉张力]

[The inhibition of medullary reticulospinal neurons during the excitation of the dorsolateral portions of the pons blocking movement and muscle tonus in rats].

作者信息

Mileĭkovskiĭ B Iu, Kiiashchenko L I, Titkov E S

机构信息

I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Acad. Sci., St. Petersburg, Russia.

出版信息

Ross Fiziol Zh Im I M Sechenova. 1999 Mar;85(3):353-9.

Abstract

Hypothalamic stimulation increasing the muscle tone in hindlimbs, and excitation of the pontine dorsolateral areas inhibiting movements and the muscle tone in rats, were studied. Hypothalamic stimulation made 36.7% of the reticulospinal neurones to discharge in the form of short-latency spikes and to increase the muscle tone. The reticulospinal cells were completely inhibited by electrical stimulation of the pontine dorsolateral areas. 23.4% of the neurones only responded to the stimulation of the pontine dorsolateral areas. 35.9% of the cells did not respond to the stimulations at all. Excitation of the pontine inhibitory areas seems to prevent the descending activating effects from the brain rostral structures to spinal motor centres.

摘要

研究了下丘脑刺激增加大鼠后肢肌张力,以及脑桥背外侧区兴奋抑制大鼠运动和肌张力的情况。下丘脑刺激使36.7%的网状脊髓神经元以短潜伏期尖峰形式放电并增加肌张力。电刺激脑桥背外侧区可完全抑制网状脊髓细胞。23.4%的神经元仅对脑桥背外侧区的刺激有反应。35.9% 的细胞对刺激完全无反应。脑桥抑制区的兴奋似乎可阻止大脑前部结构对脊髓运动中枢的下行激活作用。

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