Abasiyanik A, Daşci Z, Duman A, Kuru N, Köseoğlu B, Gündoğlu B, Abasiyanik F, Beşoluk K
Department of Pediatric Surgery, Medical Faculty, Selçute University, Konya, Turkey.
Res Exp Med (Berl). 1999 Jul;199(1):29-34. doi: 10.1007/s004330050130.
The aim of this study was to prevent the complications of gastrocystoplasty by using reversed seromuscular gastrocystoplasty for bladder augmentation. Healthy mongrel dogs were used in the study. A diamond shaped segment was separated from the remainder of the stomach preserving the right gastroepiploic artery in 11 dogs. The gastric mucosa was removed. A reversed seromuscular gastrocystoplasty was performed. The animals were observed for a mean of 7.7 months. Thereafter, relaparotomy was performed in all animals. A bladder stone was found in 1 dog. In the histopathological evaluation of the urinary bladder, it was seen that the gastric serosal surface was covered with the urothelium in all dogs. Transitional epithelial hyperplasia in 1 dog (12.5%) and squamous metaplasia in 2 dogs (25%) were identified. There were no statistical differences between preoperative and postoperative values of urine and blood pH and serum sodium, potassium, chloride, and bicarbonate levels. Complications of gastrocystoplasty such as hypochloremic metabolic alkalosis and hematuria and dysuria syndrome, are prevented by this procedure. The shrinkage of the gastric patch surface may also be prevented by facing the smooth gastric serosa to the internal surface of the urinary bladder.
本研究的目的是通过使用逆行浆肌层胃膀胱扩大术来预防胃膀胱扩大术的并发症。研究中使用了健康的杂种犬。在11只犬中，从胃的其余部分分离出一个菱形节段，保留胃网膜右动脉。去除胃黏膜。进行逆行浆肌层胃膀胱扩大术。对动物进行了平均7.7个月的观察。此后，对所有动物进行再次剖腹手术。在1只犬中发现膀胱结石。在膀胱的组织病理学评估中，发现所有犬的胃浆膜表面均被尿路上皮覆盖。确定1只犬（12.5%）有移行上皮增生，2只犬（25%）有鳞状化生。术前和术后尿液及血液pH值以及血清钠、钾、氯和碳酸氢盐水平之间无统计学差异。该手术可预防胃膀胱扩大术的并发症，如低氯性代谢性碱中毒、血尿和排尿困难综合征。通过使光滑的胃浆膜面向膀胱内表面，也可防止胃补片表面的收缩。
