Onsurbe Ramírez I, Hernández Rodríguez M, Aparicio Meix J M, Carrascosa Romero C
Sección de Neuropediatría, Hospital General de Albacete.
An Esp Pediatr. 1999 Aug;51(2):154-8.
The purpose of this study was to determine the incidence rate and the relative frequency of epilepsy and epileptic syndromes during childhood in the province of Albacete.
Patients with childhood epilepsy living in the area have been diagnosed in the Neuropediatric Unit at the General Hospital of Albacete. We included patients under 11 years of age with unprovoked recurring epileptic seizures whose first seizure happened between 1-1-1987 and 1-12-1991, excluding those who have only suffered from febrile seizures and other provoked epileptic seizures.
In the five-year period of the study, 136 patients from a population of 60,000 children under 11 years of age suffered from epilepsy. The annual incidence rate of epilepsy at this age is 45 in 100,000. For those under 1 year it is 113, for those aged 1 to 5 it is 52, and for those between 6 and 10 years 30. The most common epileptic syndrome is benign childhood epilepsy with centrotemporal spikes (29%), followed by undefined generalized idiopathic epilepsy (16%), symptomatic partial epilepsy (15%) and childhood absence epilepsy (9%).
The epilepsy incidence rates reported here are lower than those found in most studies. Nevertheless, these results agree with some more recent studies. Benign childhood epilepsy with centrotemporal spikes is the most frequent epileptic syndrome during childhood.
本研究旨在确定阿尔瓦塞特省儿童期癫痫及癫痫综合征的发病率和相对频率。
居住在该地区的儿童癫痫患者在阿尔瓦塞特综合医院的神经儿科病房被诊断。我们纳入了11岁以下无诱因反复发作癫痫发作的患者,其首次发作发生在1987年1月1日至1991年12月1日之间,不包括仅患有热性惊厥和其他诱发性癫痫发作的患者。
在研究的五年期间,60000名11岁以下儿童中有136名患有癫痫。这个年龄段癫痫的年发病率为十万分之45。1岁以下儿童为十万分之113,1至5岁儿童为十万分之52,6至10岁儿童为十万分之30。最常见的癫痫综合征是伴有中央颞部棘波的良性儿童癫痫(29%),其次是未明确的全身性特发性癫痫(16%)、症状性部分性癫痫(15%)和儿童失神癫痫(9%)。
这里报告的癫痫发病率低于大多数研究中的发病率。然而,这些结果与一些近期研究一致。伴有中央颞部棘波的良性儿童癫痫是儿童期最常见的癫痫综合征。