Rayes A A, Lambertucci J R
Departamento de Clínica Medica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte.
Rev Soc Bras Med Trop. 1999 Jul-Aug;32(4):425-38. doi: 10.1590/s0037-86821999000400014.
The association between hepatic abscesses and schistosomiasis mansoni was confirmed by clinical and experimental studies. Other parasites may cause systemic immunologic changes and local structural alterations in the affected organs that can facilitate the seeding of these areas by bacteria. Tropical pyomyositis, pyogenic liver and renal abscesses are frequent diseases in tropical areas. The visceral larva migrans syndrome is caused by the presence, in the human body, of larvae of worms that have other animals as their definitive host, most commonly being caused by Toxocara canis. The larvae migrate to various body organs leading to many inflammatory reactions in the form of granuloma and tissue necrosis. In this review we discuss the possible host-parasite-bacteria interactions that would favour the formation of abscesses in the organs involved by the larva of T. canis and present preliminary results of a clinical and experimental study undertaken during the last four years to define the role of this parasite in the pathogenesis of the abscesses.
临床和实验研究证实了肝脓肿与曼氏血吸虫病之间的关联。其他寄生虫可能会引起全身免疫变化以及受影响器官的局部结构改变,从而便于细菌在这些部位定植。热带脓性肌炎、化脓性肝脓肿和肾脓肿是热带地区的常见疾病。内脏幼虫移行症候群是由人体中以其他动物为终宿主的蠕虫幼虫引起的,最常见的是犬弓首蛔虫。幼虫迁移至身体各个器官,导致许多以肉芽肿和组织坏死形式出现的炎症反应。在本综述中,我们讨论了可能有利于犬弓首蛔虫幼虫所累及器官形成脓肿的宿主 - 寄生虫 - 细菌相互作用,并展示了过去四年进行的一项临床和实验研究的初步结果,以确定这种寄生虫在脓肿发病机制中的作用。