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精神分裂症的洞察:其与执行功能测量的关系。

Insight in schizophrenia: its relationship to measures of executive functions.

作者信息

Mohamed S, Fleming S, Penn D L, Spaulding W

机构信息

Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa, Iowa City 52242-1057, USA.

出版信息

J Nerv Ment Dis. 1999 Sep;187(9):525-31. doi: 10.1097/00005053-199909000-00001.

Abstract

Lack of awareness of specific symptoms among persons with schizophrenia has not been adequately studied in the context of neuropsychological function. The purpose of this study is to investigate whether poor insight as measured by the Scale to Assess Unawareness of Mental Disorder is empirically related to performance measures having a known association with executive functions in a group of individuals with chronic schizophrenia. The results showed that unawareness and misattribution of negative symptoms are significantly associated with deficits in some aspects of executive functioning even after a test of general intelligence had been partialed from the analyses. We conclude that unawareness of negative symptoms is associated with executive functioning in individuals with chronic schizophrenia. Unawareness of other symptoms (i.e., positive symptoms) may reflect dysfunction in other types of neuropsychological processes, or it may reflect motivation to deceive oneself or others.

摘要

在神经心理学功能的背景下,尚未对精神分裂症患者对特定症状的认识不足进行充分研究。本研究的目的是调查,在一组慢性精神分裂症患者中,以精神障碍自知力评估量表所衡量的自知力差是否与已知与执行功能相关的表现指标存在实证关联。结果表明,即使在分析中剔除了一般智力测试的影响,阴性症状的自知力缺乏和错误归因仍与执行功能某些方面的缺陷显著相关。我们得出结论,阴性症状的自知力缺乏与慢性精神分裂症患者的执行功能有关。对其他症状(即阳性症状)的自知力缺乏可能反映了其他类型神经心理过程的功能障碍,或者可能反映了自我欺骗或欺骗他人的动机。

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