Venkatesh K S, Ramanujam P
Surgical Department, Desert Samaritan Hospital, Mesa, Arizona, USA.
Dis Colon Rectum. 1999 Sep;42(9):1136-9. doi: 10.1007/BF02238564.
This prospective study was done to analyze the efficacy of autologous fibrin glue application in the healing or closure of recurrent anorectal fistulas. Autologous cryoprecipitate was used as fibrin glue in all patients. This group included complex anorectal fistulas, rectovaginal fistulas, and urethrovesicorectal fistulas.
Patients were given bowel preparation and intravenous antibiotics before the procedure. Fistulas were curetted before injection of fibrin glue.
Overall success rate was 60 percent. Patients with fistulas associated with acquired immunodeficiency syndrome and the urinary tract failed to respond. No major complications were encountered.
The results of fibrin glue use in this small series of recurrent fistulas is appealing. This use of fibrin glue can be done as an outpatient procedure as a minimally invasive technique, without any significant complications. It can be offered as an alternative to conventional surgery in recurrent fistulas.
本前瞻性研究旨在分析自体纤维蛋白胶应用于复发性肛肠瘘愈合或闭合的疗效。所有患者均使用自体冷沉淀作为纤维蛋白胶。该组包括复杂性肛肠瘘、直肠阴道瘘和尿道膀胱直肠瘘。
术前对患者进行肠道准备并给予静脉抗生素。在注射纤维蛋白胶之前对瘘管进行刮除。
总体成功率为60%。与获得性免疫缺陷综合征和泌尿道相关的瘘管患者无反应。未发生重大并发症。
在这一小系列复发性瘘管中使用纤维蛋白胶的结果很有吸引力。这种纤维蛋白胶的应用可作为门诊手术，作为一种微创技术，无任何重大并发症。它可以作为复发性瘘管传统手术的替代方法。
