Calabrese L
Casa di Cura Val Parma, Longhirano.
Acta Biomed Ateneo Parmense. 1998;69(3-4):113-21.
The carcinoma in situ of the breast is a noninvasive variant of breast cancer which has an favorable prognosis with appropriate management. The widespread use of mammography has contributed to its increased rate of diagnosis. Special attention to the problem of in situ carcinoma is justified by the increasing frequency of its recognition and the controversy surrounding the proper treatment. Carcinoma in situ (CIS) of the breast can be divided in two categories, depending on where it arises: ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS). The two histologic kinds of this cancer have distinct pathologic and biologic characteristics, with different therapeutic implication. The author, on the basis of literature on the topic, reviews present studies of DCIS and LCIS with a particular care for the pathology, the diagnostic approaches and the current treatment of these tumors.
乳腺原位癌是乳腺癌的一种非侵袭性变体，经过适当治疗预后良好。乳腺钼靶摄影的广泛应用导致其诊断率上升。原位癌问题受到特别关注是合理的，因为其被识别的频率不断增加，且围绕恰当治疗存在争议。乳腺原位癌（CIS）可根据其起源部位分为两类：导管原位癌（DCIS）和小叶原位癌（LCIS）。这种癌症的两种组织学类型具有不同的病理和生物学特征，治疗意义也不同。作者基于该主题的文献，对DCIS和LCIS的现有研究进行综述，特别关注这些肿瘤的病理学、诊断方法和当前治疗。
