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异质人群中的肾移植:蒙特菲奥里医疗中心三十年经验

Renal transplantation in a heterogeneous population: the thirty-year Montefiore Medical Center experience.

作者信息

Greenstein S M, Kim D, Principe A, Ong E, Chin W, Glicklich D, Schechner R, Tellis V

机构信息

Montefiore Medical Center-Albert Einstein College of Medicine, Bronx, New York, USA.

出版信息

Clin Transpl. 1998:187-93.

PMID:10503097
Abstract

Based on more than 30 years of renal transplantation experience at Montefiore Medical Center we conclude: 1. Improved patient and graft survival can be achieved in the cadaveric transplant recipient despite increasing co-morbidities. 2. Patients at the extremes of age (< 10 or > 60) can undergo renal transplantation safely, with patient and graft survival rates approaching those of the general recipient population. 3. Results of transplantation in African-Americans are as good as non African-Americans at 3 years. Beyond that point the graft survival curves diverge. Well matched (0-1 HLA mismatches) kidneys in the African-American patient do as well if not better than other ethnic groups. However, African-Americans do not receive as many well matched kidneys as others.

摘要

基于蒙特菲奥里医疗中心30多年的肾移植经验,我们得出以下结论:1. 尽管合并症增多,但尸体肾移植受者的患者及移植物存活率仍可提高。2. 年龄极端的患者(<10岁或>60岁)可安全地接受肾移植,其患者及移植物存活率接近一般受者人群。3. 非裔美国人肾移植3年的结果与非非裔美国人一样好。超过这一阶段,移植物存活曲线出现分化。非裔美国患者中HLA错配为0-1个的匹配良好的肾脏,即便不比其他种族群体更好,至少也一样好。然而,非裔美国人获得的匹配良好的肾脏数量不如其他种族。

相似文献

1
Renal transplantation in a heterogeneous population: the thirty-year Montefiore Medical Center experience.异质人群中的肾移植:蒙特菲奥里医疗中心三十年经验
Clin Transpl. 1998:187-93.
2
Kidney transplantation at the University of Miami.迈阿密大学的肾脏移植
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3
The UNOS Scientific Renal Transplant Registry.美国器官共享联合网络科学肾脏移植登记处。
Clin Transpl. 1996:1-14.
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The UNOS Scientific Renal Transplant Registry.美国器官共享联合网络科学肾脏移植登记处。
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The LifeLink Foundation and cadaver kidney transplantation in Tampa.生命链接基金会与坦帕的尸体肾移植
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6
Fifteen-year experience with pediatric renal transplantation at the Montefiore Medical Center.蒙特菲奥里医疗中心15年小儿肾移植经验。
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Renal retransplantation at the University of Alabama at Birmingham: incidence and outcome.
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Kidney transplantation, the Halifax experience.肾移植:哈利法克斯的经验
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The center effect: is bigger better?中心效应:越大越好吗?
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Factors influencing long-term primary cadaveric kidney transplantation--importance of functional renal mass versus avoidance of acute rejections--the Toronto Hospital experience 1985-1997.影响尸体供肾长期原位移植的因素——功能性肾质量的重要性与避免急性排斥反应——多伦多医院1985 - 1997年的经验
Clin Transpl. 1998:195-203.

引用本文的文献

1
Ethnic advantages in kidney transplant outcomes: the Hispanic Paradox at work?肾移植结果中的种族优势:西班牙裔悖论在起作用?
Nephrol Dial Transplant. 2009 Apr;24(4):1103-9. doi: 10.1093/ndt/gfn691. Epub 2008 Dec 15.