Auerbach K G
IBCLC, The Parent Center, Ferndale, WA 98248, USA.
J Obstet Gynecol Neonatal Nurs. 1999 Sep-Oct;28(5):554-63. doi: 10.1111/j.1552-6909.1999.tb02029.x.
Drug therapy during lactation requires recognition of several elements, including drug properties, the status of the infant, the mother's milk production, and what is known about particular drugs. It is important to consider the various properties of a drug when evaluating its possible effects in the breastfeeding infant. In addition, the volume of milk the infant receives and its composition can influence exposure levels. Other factors of importance include the infant's age, frequency of feedings, recommended drug dosage, and whether the drug is short- or long-acting. Suggestions are offered for appropriate drug therapy when the mother is breastfeeding, including the safety of drugs commonly administered during lactation and questions to ask when a mother seeks assistance about suggested medication use.
哺乳期的药物治疗需要考虑多个因素,包括药物特性、婴儿状况、母亲的乳汁分泌情况以及特定药物的相关知识。在评估药物对母乳喂养婴儿可能产生的影响时,考虑药物的各种特性非常重要。此外,婴儿摄入的乳汁量及其成分会影响药物暴露水平。其他重要因素包括婴儿的年龄、喂养频率、推荐的药物剂量以及药物是短效还是长效。文中提供了母亲母乳喂养时适当药物治疗的建议,包括哺乳期常用药物的安全性以及母亲寻求药物使用建议帮助时应询问的问题。