Patak M A, Weishaupt D, Fröhlich J M, Debatin J F
Institute of Diagnostic Radiology, University Hospital Zurich, CH-8091 Zurich, Switzerland.
J Magn Reson Imaging. 1999 Sep;10(3):474-6. doi: 10.1002/(sici)1522-2586(199909)10:3<474::aid-jmri32>3.0.co;2-q.
A magnetic resonance image (MRI)-based method to determine the colonic transit time is described. It is based on the oral ingestion of a single dose of 4 ml Gd-DOTA following an overnight fast and the subsequent acquisition of fast three-dimensional (3D) gradient-echo sequences under apnea conditions. The technique was successfully evaluated in three healthy volunteers. Transit of the contrast agent through the small and large intestines was easily followed. Thus, MRI-based colonic transit time determinations are feasible.
描述了一种基于磁共振成像（MRI）的测定结肠传输时间的方法。该方法基于在禁食过夜后口服单剂量4毫升钆喷酸葡胺（Gd-DOTA），随后在屏气条件下采集快速三维（3D）梯度回波序列。该技术在三名健康志愿者中成功进行了评估。造影剂在小肠和大肠中的传输很容易追踪。因此，基于MRI测定结肠传输时间是可行的。
