Stubbs G
Department of Molecular Biology, Vanderbilt University, Box 1820, Station B, Nashville, TN 37235, USA.
Curr Opin Struct Biol. 1999 Oct;9(5):615-9. doi: 10.1016/s0959-440x(99)00014-7.
Improved specimen preparation methods, third generation synchrotron sources, new data processing algorithms and molecular dynamics refinement techniques are, together, allowing the high-resolution structure determination of larger and larger macromolecular complexes by fiber diffraction. New synchrotron sources are also making possible both time-resolved studies and studies of ordered fibers only a few microns in diameter.