Lindqvist P, Dahlbäck B, Marŝál K
Department of Obstetrics and Gynecology, and Coagulation Research, University of Lund, University Hospital, Sweden.
Obstet Gynecol. 1999 Oct;94(4):595-9. doi: 10.1016/s0029-7844(99)00308-7.
To determine the incidence of pregnancy-related venous thromboembolic events and the relationship to selected risk factors such as maternal age, parity, smoking, preeclampsia, or cesarean delivery.
All Swedish women reported as having pregnancy-related venous thromboembolic events during 1990-1993 (608 of 479,422 deliveries) were compared with all thrombosis-free Swedish pregnant women during 1993 (114,940).
The incidence of pregnancy-related venous thromboembolic events was 13 per 10,000 deliveries. Cesarean delivery was associated with a fivefold increased risk of venous thromboembolic events. Advanced age was not a significant risk factor itself, but was associated with an age-related increase in frequency of cesareans. Women with preeclampsia were at a threefold higher risk postpartum, but at no increased risk before delivery. There was a tobacco consumption-dependent increase in the risk of thrombosis among smokers.
The incidence of pregnancy-related thrombosis was 13 per 10,000 and provided new insights to important risk factors such as age, cesarean delivery, smoking, and preeclampsia.
确定妊娠相关静脉血栓栓塞事件的发生率及其与选定风险因素（如产妇年龄、产次、吸烟、先兆子痫或剖宫产）之间的关系。
将1990 - 1993年期间报告发生妊娠相关静脉血栓栓塞事件的所有瑞典女性（479,422例分娩中的608例）与1993年所有无血栓形成的瑞典孕妇（114,940例）进行比较。
妊娠相关静脉血栓栓塞事件的发生率为每10,000例分娩中有13例。剖宫产与静脉血栓栓塞事件风险增加五倍相关。高龄本身并非显著风险因素，但与剖宫产频率随年龄增加有关。先兆子痫女性产后风险高三倍，但分娩前无风险增加。吸烟者血栓形成风险随烟草消费量增加。
妊娠相关血栓形成的发生率为每10,000例中有13例，并为年龄、剖宫产、吸烟和先兆子痫等重要风险因素提供了新见解。
