[中国人群中5号染色体与哮喘的连锁分析]
[Linkage analysis of chromosome 5 and asthma in a Chinese population].
作者信息
Luo J, Ji Y, Peng Y, Xiao J, Yao Y, Xu H, Yang M, Zhen J, Lu D, Jin L
机构信息
Jingan Clinical Immunology Research Center, Jingan Qu Central Hospital, Shanghai, 200040, P.R. China.
出版信息
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 1999 Oct;16(5):318-20.
PMID:10514541
Abstract
OBJECTIVE
To investigate the linkage between asthma and 5q31-33 in a Chinese population.
METHODS
The linkage between microsatellite markers in 5q and asthma and allergy was tested by lod score analysis.
RESULTS
The linkage between asthma and 5q31-33 was not confirmed.
CONCLUSION
The genes at 5q31-33 are not likely to contribute to inheritance of asthma in this Chinese population.
摘要
目的
在中国人群中研究哮喘与5q31 - 33之间的连锁关系。
方法
通过对数优势计分分析检测5q区域微卫星标记与哮喘及过敏之间的连锁关系。
结果
哮喘与5q31 - 33之间的连锁关系未得到证实。
结论
在该中国人群中，5q31 - 33区域的基因不太可能导致哮喘的遗传。
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