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The role of nonprincipal cells in dentate gyrus excitability and its relevance to animal models of epilepsy and temporal lobe epilepsy.

作者信息

Scharfman H E

机构信息

Helen Hayes Hospital, New York State Department of Health, West Haverstraw, USA.

出版信息

Adv Neurol. 1999;79:805-20.

PMID:10514865
Abstract
摘要

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Adv Neurol. 1999;79:805-20.
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Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease.在生命早期补充胆碱可以改善认知功能,而胆碱水平低则会损害阿尔茨海默病小鼠模型的结果。
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Adult neurogenesis in the mouse dentate gyrus protects the hippocampus from neuronal injury following severe seizures.成年小鼠齿状回神经发生可保护海马神经元免受严重癫痫发作后的损伤。
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Front Cell Neurosci. 2018 Jun 26;12:167. doi: 10.3389/fncel.2018.00167. eCollection 2018.