Durst J, Heller W, Hausdoerfer J, Schmidt K
Resuscitation. 1976;5(3):191-5. doi: 10.1016/0300-9572(76)90043-5.
Experimental studies and pathological investigations indicate that intrusion of fat into the circulation is common after trauma. This may not have any effect unless frank hypovolaemia supervenes upon changes in the blood vessels, manifested by a deficient vasomotility in shock. After fat embolism disseminated intravascular coagulopathy may occur as a consequence of the haematological changes and disturbances of capillaries. The morphological appearance of massive post-traumatic fat embolism evolves from the compensatory effect of accumulated synergistic factors that primarily induced the changes. From this point of view fat embolism should be recognized in the additional important role of an epiphenomenon of post-traumatic shock.
实验研究和病理学调查表明，创伤后脂肪进入循环系统的情况很常见。除非出现明显的低血容量，并叠加血管变化，表现为休克时血管运动功能不足，否则这可能不会产生任何影响。脂肪栓塞后，由于血液学变化和毛细血管紊乱，可能会发生弥散性血管内凝血。创伤后大量脂肪栓塞的形态学表现是由主要引发这些变化的累积协同因素的代偿作用演变而来的。从这个角度来看，脂肪栓塞应被视为创伤后休克附带现象的另一个重要作用。
