Luca S, Romeo S
Cattedra e Scuola di Specializzazione, Chirurgia Vascolare, Ospedale Garibaldi, Università degli Studi, Catania.
Minerva Cardioangiol. 1999 Jun;47(6):219-22.
Nifedipine, as most calcium-antagonist drugs, is widely used for the treatment of angina pectoris and primary hypertension. Among its side effects, edema of lower limbs may expose patients to traumatic ulcers which become chronic. A case with painful ulcers and remarkable swelling of the ankles is reported. In this case, misdiagnosed as chronic venous insufficiency, good results were obtained with topical treatment and discontinuation of nifedipine. Leg ulcers and edema resolved in four months after ten years of disease history.
硝苯地平与大多数钙拮抗剂药物一样，广泛用于治疗心绞痛和原发性高血压。在其副作用中，下肢水肿可能使患者出现创伤性溃疡并发展为慢性溃疡。本文报告了一例伴有疼痛性溃疡和踝关节明显肿胀的病例。该病例最初被误诊为慢性静脉功能不全，经局部治疗和停用硝苯地平后取得了良好效果。在有十年病史的情况下，腿部溃疡和水肿在四个月后消退。
