Godeau B, Bierling P
Service de médecine interne I, Hôpital Henri-Mondor, Créteil, France.
Rev Med Interne. 1999;20 Suppl 4:440s-443s. doi: 10.1016/s0248-8663(00)88676-2.
To determine the usefulness of intravenous immunoglobulin in the treatment of autoimmune thrombocytopenic purpura (AITP).
IVIg infusion is an important agent in managing AITP because most patients experienced a rapid increased platelet count. Its precise place in the management of these patients is however controversial, particularly on account of its high cost and transient effect. It is indicated in the severe form of the disease or before surgery in corticoresistant patients.
Prospective studied are mandatory to compare the efficacy of IVIg and high dose corticosteroids in this indication.
确定静脉注射免疫球蛋白在自身免疫性血小板减少性紫癜(AITP)治疗中的效用。
静脉注射免疫球蛋白输注是治疗AITP的一种重要药物,因为大多数患者血小板计数迅速增加。然而,它在这些患者治疗中的准确地位存在争议,尤其是因其高成本和短暂疗效。它适用于疾病的严重形式或对皮质类固醇耐药患者的术前治疗。
必须进行前瞻性研究以比较静脉注射免疫球蛋白和高剂量皮质类固醇在该适应症中的疗效。