Guarnelli M E, Trombelli L, Calura G
Department of Medical and Surgical Discipline of Communication and Behaviour Clinical Dentistry Section, University of Ferrara.
Minerva Stomatol. 1999 Jun;48(6):247-55.
This prospective case-control study was performed to assess alveolar bone height in HIV-positive and HIV-negative patients.
Twenty-three HIV-positive patients, 16 men and 7 women, aged 24 to 40 years (mean age: 33 years), consecutively referred to the Dental Clinic, University of Ferrara, for clinical and radiographic assessment of oral conditions, were included in the study (test group). All patients had undergone laboratory evaluation to assess HIV-infection status and were classified according to CDC diagnostic criteria. Nineteen patients were intravenous drug abusers. Thirty-four HIV-negative subjects were matched for demographic characteristics and smoking status as a control group. Radiographic evaluation was based on panoramic radiography and bone measurements were limited to premolars and molars. Alveolar bone height was measured mesially and distally to each tooth and determined as the distance from the apex of the root to a point where the lamina dura became continuous with the compact bone of the interdental septum. Alveolar bone height was recorded as well as the ratio between alveolar bone height and tooth length.
The results indicated a tendency for a difference in alveolar bone height between groups, lower in the test group compared to controls. However, this difference only reached statistical significance on a tooth-specific basis.
In conclusion, the results show a greater trend for alveolar bone loss of posterior teeth in HIV-positive patients compared to HIV-negative patients.
本前瞻性病例对照研究旨在评估HIV阳性和HIV阴性患者的牙槽骨高度。
连续转诊至费拉拉大学牙科诊所进行口腔状况临床和影像学评估的23名HIV阳性患者(16名男性和7名女性,年龄24至40岁,平均年龄:33岁)被纳入研究(试验组)。所有患者均接受了实验室评估以评估HIV感染状况,并根据美国疾病控制与预防中心(CDC)诊断标准进行分类。19名患者为静脉吸毒者。34名HIV阴性受试者作为对照组,根据人口统计学特征和吸烟状况进行匹配。影像学评估基于全景X线片,骨测量仅限于前磨牙和磨牙。测量每颗牙齿近中和远中的牙槽骨高度,并将其确定为从牙根尖到硬骨板与牙间间隔致密骨连续的点的距离。记录牙槽骨高度以及牙槽骨高度与牙长的比值。
结果表明两组之间牙槽骨高度存在差异的趋势,试验组低于对照组。然而,这种差异仅在特定牙齿的基础上达到统计学意义。
总之,结果显示与HIV阴性患者相比,HIV阳性患者后牙牙槽骨丧失的趋势更大。