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[小剂量阿苯达唑治疗肝包虫病的疗效:病例报告]

[Efficacy of low-dose albendazole therapy in hydatic liver disease: a case report].

作者信息

Prokopowicz D, Puzanowska B, Sokolewicz-Bobrowska E, Grzeszczuk A

机构信息

Kliniki Obserwacyjno-Zakaźnej Akademii Medycznej w Białymstoku.

出版信息

Pol Merkur Lekarski. 1999 Jul;7(37):23-4.

PMID:10522408
Abstract

Hydatid liver disease is the most common form of human echinococcosis in Poland. Epidemiological data show a rising number of cases recognised last years. It is probably because of easier availability of ultrasound examination and computed tomography in the diagnostic procedures. While surgery remains the only approach for a radical cure, the chemotherapy with albendazole has became a useful advance in the management of cystic echinococcosis for the problem patient (inoperable disease, widely disseminated cysts, high surgical risk, etc.). The authors describe a patient with hydatid liver disease successfully treated with albendazole as a alternative treatment to surgery. A cyclic treatment of 28 days with 2 week break in between for 9 months with low doses of albendazole (6 mg/kg) resulted in clinical improvement and involution of hepatic cysts.

摘要

肝包虫病是波兰人类棘球蚴病最常见的形式。流行病学数据显示,过去几年确诊的病例数呈上升趋势。这可能是因为在诊断过程中更容易获得超声检查和计算机断层扫描。虽然手术仍然是根治的唯一方法,但对于问题患者(无法手术的疾病、广泛播散的囊肿、手术风险高等等),使用阿苯达唑进行化疗已成为囊性棘球蚴病治疗中的一项有益进展。作者描述了一名肝包虫病患者成功接受阿苯达唑治疗,作为手术的替代治疗方法。采用低剂量阿苯达唑(6毫克/千克)进行为期28天的循环治疗,中间休息2周,持续9个月,结果临床症状改善,肝囊肿缩小。

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Pol Merkur Lekarski. 1999 Jul;7(37):23-4.
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