The interaction of nitric oxide, bradykinin, and the angiotensin II type 2 receptor: lessons learned from transgenic mice.
作者信息
Searles C D, Harrison D G
机构信息
Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
出版信息
J Clin Invest. 1999 Oct;104(8):1013-4. doi: 10.1172/JCI8507.
Abstract
摘要
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本文引用的文献
1
Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation.血管紧张素II 2型受体过表达激活血管激肽系统并导致血管舒张。
J Clin Invest. 1999 Oct;104(7):925-35. doi: 10.1172/JCI7886.
2
Modulation of vascular development and injury by angiotensin II.血管紧张素II对血管发育和损伤的调节作用
Cardiovasc Res. 1999 Mar;41(3):689-700. doi: 10.1016/s0008-6363(98)00267-3.
3
The AT2 receptor: fact, fancy and fantasy.
Regul Pept. 1999 May 31;81(1-3):11-24. doi: 10.1016/s0167-0115(99)00023-3.
4
AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism.血管紧张素Ⅱ 2型受体刺激通过激肽依赖性机制增加自发性高血压大鼠脑卒中倾向型大鼠的主动脉环磷酸鸟苷水平。
Hypertension. 1998 Jan;31(1 Pt 2):349-55. doi: 10.1161/01.hyp.31.1.349.
5
Downregulation of angiotensin II type 1 receptor gene transcription by nitric oxide.一氧化氮对血管紧张素II 1型受体基因转录的下调作用
Hypertension. 1998 Jan;31(1 Pt 2):342-8. doi: 10.1161/01.hyp.31.1.342.
6
Angiotensin type 2 receptors are reexpressed by cardiac fibroblasts from failing myopathic hamster hearts and inhibit cell growth and fibrillar collagen metabolism.2型血管紧张素受体在患有心肌病的衰竭仓鼠心脏的心脏成纤维细胞中重新表达，并抑制细胞生长和纤维状胶原代谢。
Circulation. 1997 Dec 2;96(11):3954-62. doi: 10.1161/01.cir.96.11.3954.
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Angiotensin type 2 receptor dephosphorylates Bcl-2 by activating mitogen-activated protein kinase phosphatase-1 and induces apoptosis.血管紧张素2型受体通过激活丝裂原活化蛋白激酶磷酸酶-1使Bcl-2去磷酸化并诱导细胞凋亡。
J Biol Chem. 1997 Jul 25;272(30):19022-6. doi: 10.1074/jbc.272.30.19022.
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The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats.2型（AT2）血管紧张素受体介导清醒大鼠肾脏一氧化氮的生成。
J Clin Invest. 1997 Jul 15;100(2):264-9. doi: 10.1172/JCI119531.
9
Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. Role of kinins and angiotensin II type 2 receptors.血管紧张素转换酶抑制剂和血管紧张素II 1型受体拮抗剂对心力衰竭大鼠的影响。激肽和血管紧张素II 2型受体的作用。
J Clin Invest. 1997 Apr 15;99(8):1926-35. doi: 10.1172/JCI119360.
10
The subtype-2 (AT2) angiotensin receptor regulates renal cyclic guanosine 3', 5'-monophosphate and AT1 receptor-mediated prostaglandin E2 production in conscious rats.2型（AT2）血管紧张素受体调节清醒大鼠肾脏中环磷酸鸟苷以及AT1受体介导的前列腺素E2的生成。
J Clin Invest. 1996 Apr 15;97(8):1978-82. doi: 10.1172/JCI118630.
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