Wilson P W
Framingham Heart Study, Boston University School of Medicine, Massachusetts 01702, USA.
Clin Cardiol. 1999 Oct;22 Suppl 5:V1-10.
Hypertension is associated with an increased risk for heart failure, stroke, and end-stage renal disease. The mechanisms involved in progression from hypertension to heart failure have been the focus of many recent studies. In addition, we have learned much from epidemiologic studies that have helped identify risk factors for hypertension and have thus provided insight into mechanisms that are involved in the pathogenesis of this disease. This paper will consider the epidemiology of both hypertension and heart failure and their relationship with left ventricular hypertrophy. In addition, results of recent clinical trials of antihypertensive agents will be reviewed.
高血压与心力衰竭、中风及终末期肾病风险增加相关。从高血压发展至心力衰竭所涉及的机制一直是近期诸多研究的重点。此外，我们从流行病学研究中也了解到很多情况，这些研究有助于识别高血压的危险因素，从而深入了解该疾病发病机制中所涉及的机制。本文将探讨高血压和心力衰竭的流行病学及其与左心室肥厚的关系。此外，还将回顾近期抗高血压药物临床试验的结果。
