Lomascolo A, Lesage-Meessen L, Labat M, Navarro D, Delattre M, Asther M
Laboratoire de biotechnologie des champignons filamenteux, Institut national de la recherche agronomique (INRA), Ecole supérieure des ingénieurs de Luminy, Faculté des sciences de Luminy, Marseille, France.
Can J Microbiol. 1999 Aug;45(8):653-7. doi: 10.1139/w99-056.
A monokaryotic strain of the white-rot fungus Pycnoporus cinnabarinus was shown to produce, in a 2-L bioreactor culture, 100 mg.L-1 benzaldehyde (bitter almond aroma) from L-phenylalanine with a productivity of 33 mg.L-1.day-1. The addition of HP20 resin, a styrene divinylbenzene copolymer highly selective for benzaldehyde, enabled an eightfold increase in the production of benzaldehyde and a twofold increase in productivity. In the presence of HP20 resin, the production of 790 mg.L-1 benzaldehyde was concomitant with the synthesis of cinnamic acid derivatives of high organoleptic notes such as cinnamaldehyde, cinnamyl alcohol, and methyl cinnamate.