Muchmore S W
Department of Structural Biology, Abbott Laboratories, D46Y, AP10, 100 Abbott Park Road, Abbott Park, IL 60064-3500, USA.
Acta Crystallogr D Biol Crystallogr. 1999 Oct;55(Pt 10):1669-771. doi: 10.1107/s0907444999010689.
Charged-coupled device (CCD) detectors have been widely accepted as detectors for collecting X-ray diffraction images. The CCD detector offers a sensitive detection system well suited for diffraction analysis and, compared with other detectors on the market, a relatively rapid system for read-out of the collected image. The two predominant markets for the CCD detector have been those in which relatively short exposure times are used, i.e. small-molecule X-ray diffraction and large-molecule crystallography at high-intensity synchrotron sources. CCD detectors have not been commonly used on rotating-anode X-ray sources for large-molecule crystallography. Comparison of the performance of the CCD detectors with commercially available image-plate detectors shows that the CCD detectors function in a similar fashion to image-plate-based detectors.
电荷耦合器件(CCD)探测器已被广泛用作收集X射线衍射图像的探测器。CCD探测器提供了一个灵敏的检测系统,非常适合衍射分析,并且与市场上的其他探测器相比,是一个相对快速的采集图像读出系统。CCD探测器的两个主要市场是那些使用相对短曝光时间的领域,即小分子X射线衍射和高强度同步辐射源下的大分子晶体学。CCD探测器在旋转阳极X射线源用于大分子晶体学方面并不常用。将CCD探测器与市售成像板探测器的性能进行比较表明,CCD探测器的功能与基于成像板的探测器类似。