Wutzler P, Sprössig M, Wenzel K P, Mücke H
Z Exp Chir. 1975;8(4):236-40.
Biologic cardiac valve substitutes were sterilized at room temperature using beta-propiolactone with a 0.5 vol.% solution within 120 minutes, with a 1.0 vol.% solution within 90 minutes, and with a 1.5 resp. 2.0 vol.% solution within 60 minutes. The physico-chemic properties of the graft can be influenced by appropriately chosen concentration and sterilizing period. Enlarged procedures for decontamination are not necessary because of the rapid dissolution of aqueous beta-propiolactone solutions.
生物心脏瓣膜替代品在室温下使用β-丙内酯进行消毒，0.5体积%的溶液消毒120分钟，1.0体积%的溶液消毒90分钟，1.5体积%或2.0体积%的溶液消毒60分钟。通过适当选择浓度和消毒时间，可以影响移植物的物理化学性质。由于β-丙内酯水溶液能快速溶解，因此无需扩大去污程序。
