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[心肺手术后的腹部并发症]

[Abdominal complications after cardiopulmonary procedures].

作者信息

González Ojeda A, Orozco Mosqueda A, Barrera Zepeda L, Fuentes Orozco C, Avalos González J, Hinojosa Alarcón F, Paredes Carlo C O, Victal Adame O

机构信息

Unidad de Investigación en Epidemiología Clínica, Hospital de Especialidades, Centro Médico Nacional de Occidente, IMSS, Guadalajara, Jalisco.

出版信息

Rev Gastroenterol Mex. 1999 Apr-Jun;64(2):61-9.

Abstract

OBJECTIVE

To know the frequency of intraabdominal complications and its impact on survival of patients submitted to cardiopulmonary bypass for common open-heart surgical procedures.

BACKGROUND

The gastrointestinal complications after cardiac surgery with cardiopulmonary bypass (CPB) have an incidence of 0.3 to 3% but mortality can exceed 60%. Despite improvements in preoperative, operative and postoperative care it has been the general impression that abdominal complications remain a significant problem.

TYPE OF STUDY

Retrospective case-control study.

MATERIAL AND METHODS

Consecutive patients submitted to cardiac surgery with CPB between March 1995 to March 1997 were included. Any gastrointestinal complication was identified as well as its diagnosis, medical or surgical management and mortality.

RESULTS

One thousand and three hundred fifty two patients were studied of which 516 (38%) were operated for coronary revascularization, 502 (37%) valvular replacement, 68 (5.2%) a combination of valvular replacement and revascularization, 144 (10.6%) correction of congenital defects and 122 (9.6%) treated of diverse problems. Forty-four patients developed complications (3.3%) and they were, postoperative intestinal ileus in 14 cases (32%), half of them had concomitant hyperamylasemia. Hepatobiliary complications represented 29.5% (13 cases). Ten patients (22.7%) developed peptic ulcer disease complicated with perforation or hemorrhage. Severe acute pancreatitis was observed in two patients as well as two with bowel necrosis. Three patients had complications considered not related to CPB as grade I liver trauma, acute appendicitis and amebic colitis. The mortality was 11/44 (25%). As a control group, 73 patients operated upon over the same time period and on the same days as the study patients were analyzed. The mortality in this group was 5/73 (6.8%). The medical history of peptic ulcer disease (< 0.01) and postoperative hemodynamic unstability (< 0.05), the use of intra-aortic balloon pump (< 0.05) and respiratory failure with prolonged ventilatory support (< 0.05) were separate statistical significant determinants for the development of postoperative abdominal complications.

CONCLUSIONS

Factors indicative of or contributing to periods of decreased end-organ perfusion appear to be significantly related to abdominal complications. Also, medical history of peptic ulcer disease represented an individual determinant of severe surgical complications as ulcer perforation and massive bleeding.

摘要

目的

了解接受体外循环进行常见心脏直视手术患者的腹腔内并发症发生率及其对生存的影响。

背景

体外循环心脏手术后的胃肠道并发症发生率为0.3%至3%,但死亡率可超过60%。尽管术前、术中和术后护理有所改善,但总体印象是腹部并发症仍然是一个重大问题。

研究类型

回顾性病例对照研究。

材料与方法

纳入1995年3月至1997年3月期间接受体外循环心脏手术的连续患者。确定任何胃肠道并发症及其诊断、内科或外科治疗及死亡率。

结果

共研究了1352例患者,其中516例(38%)接受冠状动脉血运重建手术,502例(37%)接受瓣膜置换手术,68例(5.2%)接受瓣膜置换和血运重建联合手术,144例(10.6%)接受先天性缺陷矫正手术,122例(9.6%)接受各种其他问题的治疗。44例患者发生并发症(3.3%),其中术后肠梗阻14例(32%),半数伴有高淀粉酶血症。肝胆并发症占29.5%(13例)。10例患者(22.7%)发生消化性溃疡病并发穿孔或出血。观察到2例严重急性胰腺炎以及2例肠坏死。3例患者发生的并发症被认为与体外循环无关,分别为I级肝外伤、急性阑尾炎和阿米巴结肠炎。死亡率为11/44(25%)。作为对照组,分析了同期与研究患者在相同日期接受手术的73例患者。该组死亡率为5/73(6.8%)。消化性溃疡病史(<0.01)、术后血流动力学不稳定(<0.05)、使用主动脉内球囊泵(<0.05)以及长时间机械通气支持的呼吸衰竭(<0.05)是术后腹部并发症发生的独立统计学显著决定因素。

结论

提示或导致终末器官灌注减少时期的因素似乎与腹部并发症显著相关。此外,消化性溃疡病史是严重手术并发症如溃疡穿孔和大出血的个体决定因素。

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