Zhang Yong-Hong, Chen Zhen-Liang, Shi Lei, Chen Zhong-Jian, Dong Xiang-Yang, Zhai Bo
Department of Cardiothoracic Surgery, Children's Hospital of Zhengzhou City, Zhengzhou, Henan 450052, P.R. China.
Exp Ther Med. 2018 May;15(5):4498-4502. doi: 10.3892/etm.2018.5963. Epub 2018 Mar 19.
The aim of the present study was to analyze risk factors of intestinal perforation following surgery for the treatment of congenital heart disease in infants and young children, and to summarize experiences of diagnosis and treatment. A total of 3,270 children, who underwent congenital heart disease surgery under extracorporeal circulation from January 2010 to July 2015, were retrospectively analyzed. Among these children, three (0.09%) developed postoperative intestinal perforation. Primary diseases were Tetralogy of Fallot (two cases) and ventricular septal defect combined with atrial septal defect (one case). The age range of the children was 6-11 months and the weight range was 7.3-8.6 kg. Furthermore, these children underwent radical surgery under general anesthesia and extracorporeal circulation in low temperatures. Abdominal symptoms appeared 4-10 days after surgery, and included poor appetite, abdominal distension, intermittent vomiting, high fever, refractory irritability, crying and shortness of breath. One case was confirmed by routine abdominal puncture and the remaining two were confirmed by the detection of free gas under the diaphragm, as revealed by abdominal X-ray. Following the diagnosis of intestinal perforation, emergency intestinal fistula surgery was performed. At 3-5 days post-surgery, the patients underwent treatment by fasting and intravenously administered parenteral nutrition. Diet was increased following recovery of bowel function. All patients recovered following active treatment and 3-4 months following hospital discharge, the fistula was successfully closed. In conclusion, a concerted effort should be made to identify intestinal perforation in infants and young children with postoperative congenital heart disease during emergency surgery. Early diagnosis and treatment may significantly improve prognosis and reduce mortality.
本研究旨在分析婴幼儿先天性心脏病手术后肠穿孔的危险因素,并总结诊断和治疗经验。回顾性分析了2010年1月至2015年7月期间在体外循环下行先天性心脏病手术的3270例患儿。其中,3例(0.09%)发生术后肠穿孔。原发病为法洛四联症(2例)和室间隔缺损合并房间隔缺损(1例)。患儿年龄范围为6 - 11个月,体重范围为7.3 - 8.6 kg。此外,这些患儿在全身麻醉和低温体外循环下接受了根治性手术。术后4 - 10天出现腹部症状,包括食欲不振、腹胀、间歇性呕吐、高热、难治性烦躁、哭闹和呼吸急促。1例经常规腹腔穿刺确诊,其余2例经腹部X线检查发现膈下游离气体确诊。确诊肠穿孔后,急诊行肠造瘘手术。术后3 - 5天,患者禁食并静脉给予肠外营养治疗。肠功能恢复后增加饮食。所有患者经积极治疗后康复,出院后3 - 4个月,瘘口成功闭合。总之,在急诊手术中应共同努力识别先天性心脏病术后婴幼儿的肠穿孔。早期诊断和治疗可显著改善预后并降低死亡率。