Mayr J M, Schober P H, Weissensteiner U, Höllwarth M E
Department of Pediatric Surgery, University of Graz, Austria, Europe.
Eur J Pediatr Surg. 1999 Aug;9(4):231-5. doi: 10.1055/s-2008-1072251.
From 1976 to 1998 we have treated 17 neonates with short-bowel syndrome. Those 8 patients who had an intact ileocecal valve as well as the total colon preserved did significantly better than the 9 children without ileocecal valve and > 50% missing colon. In addition to the length of the intestinal remnants, motility had a major impact on the incidence of complications and final outcome. Four patients died (23.5%). All of them had an intestinal length of less than 30 cm, severe dysmotility, no ileocecal valve and an incomplete colon. The average duration of hospitalization of the children weaned from parenteral nutrition (n = 11) was 8.5 months. The majority of them still need supplementation of vitamins and/or trace elements. Two children suffer from recurrent d-lactic acidemia. Six children have a significant psychomotor developmental delay with three suffering from congenital cerebral abnormalities.
1976年至1998年期间，我们共治疗了17例短肠综合征新生儿。8例保留了完整回盲瓣及全结肠的患儿，其治疗效果明显优于9例未保留回盲瓣且结肠缺失超过50%的患儿。除了肠管残余长度外，肠道蠕动对并发症发生率及最终结局也有重大影响。4例患儿死亡（23.5%）。他们的肠管长度均小于30 cm，存在严重的蠕动功能障碍，无回盲瓣且结肠不完整。成功停用肠外营养的11例患儿的平均住院时间为8.5个月。他们中的大多数仍需补充维生素和/或微量元素。2例患儿患有复发性d-乳酸血症。6例患儿存在明显的精神运动发育迟缓，其中3例患有先天性脑部异常。
