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深冻保存的耳软骨同种异体移植修复对骨关节炎绵羊颞下颌关节的短期影响

Short-term effect of deep-frozen stored auricular cartilage allograft repair on the osteoarthritic sheep temporomandibular joint.

作者信息

Ogi N, Kurita K, Ishimaru J, Goss A N

机构信息

Second Department of Oral and Maxillofacial Surgery, Aichi-Gakuin University School of Dentistry, Nagoya, Japan.

出版信息

Int J Oral Maxillofac Surg. 1999 Oct;28(5):393-7.

PMID:10535546
Abstract

The initial effect of deep-frozen stored auricular cartilage replacement was tested on the progression of experimentally induced osteoarthritis in sheep. Bilateral osteoarthritis was induced in the sheep temporomandibular joint. Three months later, discectomy and deep-frozen auricular cartilage allograft repair were performed unilaterally, with the other side being left as a control. Six months post induction of osteoarthritis, 3 months post repair, the sheep were killed. The stored auricular cartilage allografts were not firmly attached to the surrounding tissue and tended to be markedly thinned and perforated. The effect of storage detrimentally affected the properties of the graft.

摘要

在绵羊实验性诱导骨关节炎进展过程中,对深冻保存的耳软骨替代物的初始效果进行了测试。在绵羊颞下颌关节诱导双侧骨关节炎。三个月后,单侧进行椎间盘切除术并用深冻耳软骨同种异体移植进行修复,另一侧作为对照。骨关节炎诱导六个月后、修复三个月后,处死绵羊。保存的耳软骨同种异体移植物未牢固附着于周围组织,且往往明显变薄和穿孔。储存的影响对移植物的性能产生了不利影响。

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引用本文的文献

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