Exelby P R, Ghandchi A, Lansigan N, Schwartz I
Cancer. 1975 Mar;35(3):826-9. doi: 10.1002/1097-0142(197503)35:3<826::aid-cncr2820350339>3.0.co;2-b.
With the increase in remission and survival in children with acute leukemia, the complication of acute abdomen has become increasingly important in the total care of these children. A total of 286 children with acute leukemia was treated at Memorial Hospital between 1966 and 1971. Sixteen or 5.6% of these children developed an acute abdomen during the course of their disease. During the same period, many other children developed symptoms and signs mimicking an acute abdomen. Of the 9 children treated surgically, 5 were long-term survivors. Two children treated conservatively died, and 5 patients were diagnosed at autopsy. Prognosis was better in those patients in remission at the time of surgery, and where remission was maintained by immediately restarting antileukemic chemotherapy. A more aggressive surgical approach to the acute abdomen, combined with careful supportive measures, is further adding to the numbers of long-term survivors in childhood leukemia.
随着急性白血病患儿缓解率和生存率的提高，急腹症并发症在这些患儿的整体护理中变得越来越重要。1966年至1971年间，纪念医院共治疗了286例急性白血病患儿。其中16例（5.6%）在病程中出现了急腹症。在同一时期，许多其他患儿出现了类似急腹症的症状和体征。接受手术治疗的9例患儿中，5例为长期存活者。2例接受保守治疗的患儿死亡，5例患者在尸检时被确诊。手术时处于缓解期且通过立即重新开始抗白血病化疗维持缓解的患者预后较好。对急腹症采取更积极的手术方法，结合精心的支持措施，进一步增加了儿童白血病长期存活者的数量。
