儿童急性白血病的治疗：基于对过去情况的推断对未来的预测。

The treatment of acute childhood leukemia: predictions for the future based on extrapolations from the past.

作者信息

Karon M

出版信息

Cancer. 1975 Mar;35(3 suppl):1000-6. doi: 10.1002/1097-0142(197503)35:3+<1000::aid-cncr2820350723>3.0.co;2-r.

DOI:10.1002/1097-0142(197503)35:3+<1000::aid-cncr2820350723>3.0.co;2-r

Abstract

Further progress in the treatment of acute leukemia involves a careful assessment of host and disease factors in each child and the selection of a therapeutic regimen which interacts with these factors to provide the maximum chance for survival. For some children, this therapy can be carried out in the community by expertly trained hematologist-oncologists; for others, the best treatment will involve clinical research at a center. Such a general approach has the best chance of fulfilling the optimistic survival projections made by the President's Cancer Panel in 1973 for acute lymphocytic leukemia.

摘要

急性白血病治疗的进一步进展涉及对每个儿童的宿主和疾病因素进行仔细评估，并选择一种能与这些因素相互作用以提供最大生存机会的治疗方案。对于一些儿童，这种治疗可由训练有素的血液肿瘤学家在社区进行；对于另一些儿童，最佳治疗将涉及在中心进行临床研究。这种总体方法最有可能实现总统癌症专题小组在1973年对急性淋巴细胞白血病所做出的乐观生存预测。