Boyd W D, Desai N D, Del Rizzo D F, Novick R J, McKenzie F N, Menkis A H
London Health Sciences Centre, University of Western Ontario, Canada.
Ann Thorac Surg. 1999 Oct;68(4):1490-3. doi: 10.1016/s0003-4975(99)00951-0.
Bypass surgery in the elderly (age >70 years) has increased mortality and morbidity, which may be a consequence of cardiopulmonary bypass. We compare the outcomes of a cohort of elderly off-pump coronary artery bypass (OPCAB) patients with elderly conventional coronary artery bypass grafting (CABG) patients.
Chart and provincial cardiac care registry data were reviewed for 30 consecutive elderly OPCAB patients (age 74.7 +/- 4.2 years) and 60 consecutive CABG patients (age 74.9 +/- 4.1 years, p = 0.82) with similar risk factor profiles: Parsonnet score 17.2 +/- 8.1 (OPCAB) versus 15.6 +/- 6.5 (CABG), p = 0.31; and Ontario provincial acuity index 4.5 +/- 1.9 (OPCAB) versus 4.3 +/- 2.0 (CABG), p = 0.65.
Mean hospital stay was 6.3 +/- 1.8 days for OPCAB patients and 7.7 +/- 3.9 days for CABG patients (p < 0.05). Average intensive care unit stay was 24.0 +/- 10.9 h for OPCAB patients versus 36.6 +/- 33.5 h for CABG patients (p < 0.05). Atrial fibrillation occurred in 10.0% of OPCAB patients and 28.3% of CABG patients (p < 0.05). Low output syndrome was observed in 10% of OPCAB patients and 31.7% of CABG patients (p < 0.05). Cost was reduced by $1,082 (Canadian) per patient in the OPCAB group. Postoperative OPCAB graft analysis showed 100% patency.
OPCAB is safe in the geriatric population and significantly reduces postoperative morbidity and cost.
老年患者(年龄>70岁)进行搭桥手术会增加死亡率和发病率,这可能是体外循环的结果。我们比较了一组老年非体外循环冠状动脉搭桥术(OPCAB)患者和老年传统冠状动脉搭桥术(CABG)患者的结局。
回顾了连续30例老年OPCAB患者(年龄74.7±4.2岁)和60例连续CABG患者(年龄74.9±4.1岁,p = 0.82)的病历和省级心脏护理登记数据,这些患者具有相似的风险因素特征:Parsonnet评分17.2±8.1(OPCAB)对15.6±6.5(CABG),p = 0.31;安大略省省级 acuity指数4.5±1.9(OPCAB)对4.3±2.0(CABG),p = 0.65。
OPCAB患者的平均住院时间为6.3±1.8天,CABG患者为7.7±3.9天(p <0.05)。OPCAB患者的平均重症监护病房住院时间为24.0±10.9小时,CABG患者为36.6±33.5小时(p <0.05)。10.0%的OPCAB患者和28.3%的CABG患者发生房颤(p <0.05)。10%的OPCAB患者和31.7%的CABG患者出现低输出量综合征(p <0.05)。OPCAB组每位患者的费用降低了1082加元(加拿大)。术后OPCAB移植物分析显示通畅率为100%。
OPCAB在老年人群中是安全的,并显著降低了术后发病率和费用。