阿帕考托迪内斯A和B：来自红色海洋藻类霍氏波蒂藻的两种四卤代单萜。

Apakaochtodenes A and B: two tetrahalogenated monoterpenes from the red marine alga Portieria hornemannii.

作者信息

Gunatilaka A A, Paul V J, Park P U, Puglisi M P, Gitler A D, Eggleston D S, Haltiwanger R C, Kingston D G

机构信息

Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24060, USA.

出版信息

J Nat Prod. 1999 Oct;62(10):1376-8. doi: 10.1021/np9901128.

DOI:10.1021/np9901128

PMID:10543896

Abstract

The structure of apakaochtodene A, the minor isomer of two tetrahalogenated ochtodene monoterpenes, isolated from the red marine alga Portieria hornemannii (Lyngbye) Silva has been identified as 6(S)-bromo-1,4(S),8(R)-trichloro-2(Z)-ochtodene (1) by NMR spectral and X-ray crystallographic analysis. Its geometrical isomer, apakaochtodene B (2), which could not be separated from 1 and thus characterized as a 95:5 mixture of 2:1 had (1)H and (13)C NMR spectral characteristics similar to previously known ochtodene (3) and the related tetrahalogenated monoterpene 4.

摘要

从红藻角叉菜（Portieria hornemannii (Lyngbye) Silva）中分离得到的两种四卤代奥克托烯单萜的次要异构体阿帕奥克托烯A的结构，经核磁共振光谱和X射线晶体学分析确定为6(S)-溴-1,4(S),8(R)-三氯-2(Z)-奥克托烯(1)。其几何异构体阿帕奥克托烯B(2)无法与1分离，因此被表征为2:1的95:5混合物，具有与先前已知的奥克托烯(3)和相关四卤代单萜4相似的(1)H和(13)C核磁共振光谱特征。