Mödder B, Blümke S, Havers W, Sehlhorst S, Haupt H
Klin Padiatr. 1975 Jan;187(1):101-7.
A case of congenital paraleucoblast-leucosis is reported. The diagnosis rested on pronounced infiltrations of the skin and leucemic signs in blood and bone marrow. The child died on the 20th day after developing signs of bleeding and cerebral involvement. At necropsy leucotic infiltration was found in may organs, mainly in pancreas, skin and bone marrow. The most prominent findings and cause of death were diffuse hemorrhagic foci with a high proportion of leucemic cells in the brain and cerebellum.
报告了一例先天性类原粒细胞白血病病例。诊断依据为皮肤的明显浸润以及血液和骨髓中的白血病体征。该患儿在出现出血和脑部受累迹象后的第20天死亡。尸检时在许多器官中发现白血病浸润，主要在胰腺、皮肤和骨髓。最显著的发现及死因是大脑和小脑出现弥漫性出血灶，其中白血病细胞比例很高。
