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营养治疗的修订与共识:炎症性肠病中的营养

[Revision and consensus in nutritional therapy: nutrition in inflammatory intestinal diseases].

作者信息

Fernández-Bañares F, Gassull Duro M A

机构信息

Servicio de Aparato Digestivo, Hospital Universitari Germans Trias i Pujol, Badalona, España.

出版信息

Nutr Hosp. 1999 May;14 Suppl 2:71S-80S.

Abstract

Energy-protein malnutrition and the sub-clinical deficiencies of vitamins and trace elements, are frequent findings in ulcerative colitis and Crohn's disease, and these may negatively influence the clinical course of these diseases. In general, the majority of the patients with ulcerative colitis and uncomplicated Crohn's disease can ingest a normal diet that is well balanced and without any restrictions. The intolerance to specific foods is rare in Crohn's disease and the application of exclusion diets in a routine manner is not indicated. When the nutritional status cannot be adequately maintained with normal ingestion, the use of artificial nutrition is indicated. Enteral nutrition is the first choice nutritional support system if the gastrointestinal tract is accessible and at least partially functional. In Crohn's disease enteral nutrition could have a specific anti-inflammatory effect ("primary treatment"), and it has been suggested that this could be effective to induce the clinical remission of the activity bouts of the disease. Some types of dietary fiber could be effective in the treatment of ulcerative colitis. Initial studies suggest their usefulness in maintaining the remission of the disease.

摘要

能量 - 蛋白质营养不良以及维生素和微量元素的亚临床缺乏,在溃疡性结肠炎和克罗恩病中很常见,这些可能会对这些疾病的临床病程产生负面影响。一般来说,大多数溃疡性结肠炎和无并发症的克罗恩病患者可以摄入正常、均衡且无任何限制的饮食。克罗恩病中对特定食物不耐受的情况很少见,常规应用排除饮食并不合适。当通过正常摄入无法充分维持营养状况时,则需使用人工营养。如果胃肠道可及且至少部分功能正常,肠内营养是首选的营养支持系统。在克罗恩病中,肠内营养可能具有特定的抗炎作用(“主要治疗”),并且有人提出这可能对诱导疾病活动期的临床缓解有效。某些类型的膳食纤维可能对溃疡性结肠炎的治疗有效。初步研究表明它们在维持疾病缓解方面有用。

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