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hMLH1 promoter hypermethylation in microsatellite instability-positive endometrial carcinoma. Cause or consequence?

作者信息

Ellenson L H

机构信息

Department of Pathology, Weill Medical College of Cornell University, New York, New York, USA.

出版信息

Am J Pathol. 1999 Nov;155(5):1399-402. doi: 10.1016/S0002-9440(10)65451-X.

DOI:10.1016/S0002-9440(10)65451-X
PMID:10550292
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1866995/
Abstract
摘要

相似文献

1
hMLH1 promoter hypermethylation in microsatellite instability-positive endometrial carcinoma. Cause or consequence?微卫星不稳定阳性子宫内膜癌中hMLH1启动子高甲基化。原因还是结果?
Am J Pathol. 1999 Nov;155(5):1399-402. doi: 10.1016/S0002-9440(10)65451-X.
2
hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis.人错配修复蛋白1(hMLH1)启动子高甲基化是人类子宫内膜肿瘤发生过程中的早期事件。
Am J Pathol. 1999 Nov;155(5):1767-72. doi: 10.1016/S0002-9440(10)65492-2.
3
hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability.散发性高频微卫星不稳定胃癌中hMLH1启动子甲基化及hMLH1表达缺失
Cancer Res. 1999 Jan 1;59(1):159-64.
4
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability.微卫星不稳定的结肠癌中hMLH1启动子的高甲基化
Cancer Res. 1998 Aug 1;58(15):3455-60.
5
Frequent hypermethylation of MLH1 promoter in normal endometrium of patients with endometrial cancers.子宫内膜癌患者正常子宫内膜中MLH1启动子频繁发生高甲基化。
Oncogene. 2003 Apr 17;22(15):2352-60. doi: 10.1038/sj.onc.1206365.
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Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability.微卫星不稳定的人类胃癌中hMLH1基因启动子的高甲基化
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Frameshift mutation at codon 642 of the hMLH1 gene in human endometrial cancer.
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Causes and consequences of microsatellite instability in endometrial carcinoma.子宫内膜癌中微卫星不稳定性的原因及后果
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[Genetic diagnosis of endometrial cancer].
Nihon Rinsho. 2004 Oct;62 Suppl 10:295-8.
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Detection of aberrantly methylated hMLH1 promoter DNA in the serum of patients with microsatellite unstable colon cancer.检测微卫星不稳定型结肠癌患者血清中异常甲基化的hMLH1启动子DNA。
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本文引用的文献

1
hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis.人错配修复蛋白1(hMLH1)启动子高甲基化是人类子宫内膜肿瘤发生过程中的早期事件。
Am J Pathol. 1999 Nov;155(5):1767-72. doi: 10.1016/S0002-9440(10)65492-2.
2
Genetic instability and the mutator phenotype. Studies in ulcerative colitis.遗传不稳定性与突变体表型。溃疡性结肠炎的研究。
Am J Pathol. 1999 Jun;154(6):1621-6. doi: 10.1016/S0002-9440(10)65415-6.
3
MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers.MLH1启动子甲基化和基因沉默是散发性子宫内膜癌微卫星不稳定的主要原因。
Hum Mol Genet. 1999 Apr;8(4):661-6. doi: 10.1093/hmg/8.4.661.
4
Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability.微卫星不稳定的人类胃癌中hMLH1基因启动子的高甲基化
Cancer Res. 1999 Mar 1;59(5):1090-5.
5
Cancer epigenetics comes of age.癌症表观遗传学已然成熟。
Nat Genet. 1999 Feb;21(2):163-7. doi: 10.1038/5947.
6
Causes and consequences of microsatellite instability in endometrial carcinoma.子宫内膜癌中微卫星不稳定性的原因及后果
Cancer Res. 1999 Jan 15;59(2):462-6.
7
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.美国国立癌症研究所微卫星不稳定性用于癌症检测和家族易感性研讨会:制定结直肠癌微卫星不稳定性测定的国际标准。
Cancer Res. 1998 Nov 15;58(22):5248-57.
8
Absence of mutations in DNA mismatch repair genes in sporadic endometrial tumors with microsatellite instability.微卫星不稳定的散发性子宫内膜肿瘤中DNA错配修复基因无突变。
Clin Cancer Res. 1996 Nov;2(11):1907-11.
9
MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas.MLH1启动子高甲基化与散发性子宫内膜癌的微卫星不稳定性表型相关。
Oncogene. 1998 Nov 5;17(18):2413-7. doi: 10.1038/sj.onc.1202178.
10
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability.微卫星不稳定的结肠癌中hMLH1启动子的高甲基化
Cancer Res. 1998 Aug 1;58(15):3455-60.