Eysel P, Rompe J, Schoenmayr R, Zoellner J
Orthopaedic University Hospital, Mainz, Germany.
Acta Neurochir (Wien). 1999;141(10):1083-7. doi: 10.1007/s007010050486.
The aim of this study is to determine the significance of an artificial nucleus implant for lumbar discs (PDN device) with special regard to the biomechanical properties of the spinal motion segment. From 11 human cadavers the lumbar segment L2/L3 was harvested, the lamina and the muscles were removed with care to preserve the anterior and posterior longitudinal ligaments. The segments were fixed on a special testing device mounted in universal testing machine (Zwick, Ulm-Germany). Physiological load with maximum of 7 Nm was applied in flexion/extension, right and left sidebending and right and left torsion. The movement of the measuring point (center of L2) was registered along three axes (sagittal, frontal and vertical axis). Three cycles of measurement were performed in all specimens: a) the intact segment, b) segment after nucleotomy, c) segment with 2 PDN devices. There was a statistically significant (p<0.05) increase in segmental mobility in all directions after nucleotomy with an increased mobility of the segment between 38 and 100 percent. After introduction of two PDN implants there was a restoration of segmental mobility for all movement-directions with no statistically significant difference compared with the intact situation before nucleotomy.
本研究的目的是确定人工椎间盘植入物（PDN 装置）对腰椎间盘的意义，特别关注脊柱运动节段的生物力学特性。从 11 具人类尸体上取下 L2/L3 腰椎节段，小心地去除椎板和肌肉，以保留前纵韧带和后纵韧带。将这些节段固定在安装在万能试验机（德国乌尔姆的 Zwick）上的特殊测试装置上。在屈伸、左右侧屈和左右扭转时施加最大 7 Nm 的生理负荷。测量点（L2 中心）的运动沿三个轴（矢状轴、额状轴和垂直轴）进行记录。对所有标本进行三个测量周期：a）完整节段，b）髓核摘除术后节段，c）植入 2 个 PDN 装置的节段。髓核摘除术后，所有方向的节段活动度均有统计学意义的增加（p<0.05），节段活动度增加 38%至 100%。植入两个 PDN 植入物后，所有运动方向的节段活动度均恢复，与髓核摘除术前的完整情况相比，无统计学显著差异。
