Marciani R D, Trodahl J M
J Oral Surg. 1975 Jun;33(6):458-61.
Cryosurgery is a proved method for treatment of neoplasms of the soft and hard tissues of the oral cavity. It is not free, however, from postoperative complications. Delayed healing and extensive scarring are common occurrences. Significant functional and esthetic impairment, although uncommon, can result. Exposure of lingual mandibular bone can interfere with prosthetic replacement. Postfreezing evaluation of cervical nodes in patients treated for oral cancers can be complicated by persistent lymphadenopathy. Cryosurgery of irradiated bone or overlying tissue can result in osteoradionecrosis. Although the possibility of these complications should not be a major deterrent when it is felt that cryosurgery is the preferred method for treating a malignancy, the complications deserve careful consideration in the management of benign lesions.
冷冻手术是治疗口腔软硬组织肿瘤的一种经证实的方法。然而，它并非没有术后并发症。愈合延迟和广泛瘢痕形成是常见情况。尽管不常见，但可能导致显著的功能和美观损害。下颌舌侧骨暴露会干扰假体置换。对接受口腔癌治疗的患者进行冷冻后颈部淋巴结评估可能会因持续性淋巴结病而变得复杂。对受照射的骨或覆盖组织进行冷冻手术可导致放射性骨坏死。尽管当认为冷冻手术是治疗恶性肿瘤的首选方法时，这些并发症的可能性不应成为主要的阻碍因素，但在处理良性病变时，这些并发症值得仔细考虑。
