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[甘氨胆酰C14呼气试验在胃手术患者细菌污染诊断中的价值]

[Value of the breath test with cholylglycine C14 in the diagnosis of bacterial contamination in patients with gastric surgery].

作者信息

Bai J C, Gándara M A, Meyer M A, Fraga A, Parera V, Boerr L, Crosetti E

出版信息

Acta Gastroenterol Latinoam. 1978 May;8(1):1-9.

PMID:105534
Abstract

The TAE C14 has been evaluated as a diagnostic method of small bowel contamination in a group of patients operated for gastric disturbances. It has been compared with bacterial culture and bile salts chromatogrpahy of jejunum liquid and therapeutic response. 36 patients have been studied and divided in 3 groups: a) negative control: 8 subjects without pathology; b) positive control: 6 patients with intestinal resection and 1 with intestinal scleroderma, all of them with steatorrhea; c) gastric operated patients: 16 BII with and without vagotomy, 3 gastroenteroanastomosis and vagotomy, 1 superselective vagotomy and pyloroplasty and 1 B I, all the patients had steatorrhea, except one with BII. The period elapsed between the operation and the studies varied from 1 to 17 years (X: 4.9 +/- 4.1). The average value of steatorrhea was 23.9 +/- 10.2 g/24 hs. 100% of group b and 80% of group c had abnormal TAE C14. In 80% of the patients of the group c chromatogrpahy was performed and it agreed with TAE C14 in 80% of the studies. Bacteriology was positive in 100% of 18 studies, coinciding with TAE C14 in 70% patients. Therapeutic control of 100% of group c was positive in 90%.

摘要

TAE C14已被评估为一种用于一组因胃部疾病接受手术的患者小肠污染的诊断方法。它已与空肠液的细菌培养、胆盐色谱分析以及治疗反应进行了比较。对36名患者进行了研究,并将其分为3组:a)阴性对照组:8名无病理的受试者;b)阳性对照组:6名接受肠切除的患者和1名患有肠硬皮病的患者,他们均有脂肪泻;c)接受胃部手术的患者:16名Billroth II式手术患者(有或无迷走神经切断术)、3名胃肠吻合术加迷走神经切断术患者、1名超选择性迷走神经切断术加幽门成形术患者以及1名Billroth I式手术患者,除1名Billroth II式手术患者外,所有患者均有脂肪泻。手术与研究之间的时间间隔为1至17年(平均值:4.9±4.1)。脂肪泻的平均值为23.9±10.2克/24小时。b组100%和c组80%的患者TAE C14异常。c组80%的患者进行了色谱分析,在80%的研究中与TAE C14结果一致。18项研究中有100%的细菌学检测呈阳性,70%的患者与TAE C14结果相符。c组100%的治疗对照中有90%呈阳性。

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