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糖尿病性神经病变患者足底溃疡风险的评估

Estimation of risk for plantar foot ulceration in diabetic patients with neuropathy.

作者信息

Sauseng S, Kästenbauer T, Sokol G, Irsigler K

机构信息

Ludwig-Boltzmann Institute for Metabolic Diseases and Nutrition, Hospital Vienna-Lainz, Austria.

出版信息

Diabetes Nutr Metab. 1999 Jun;12(3):189-93.

Abstract

The main risk factors for plantar forefoot ulcers are loss of protective sensation due to sensory neuropathy and increased mechanical stress on the sole of the foot. The aim of this study was to find a better parameter than the plantar pressure to explain the occurrence of plantar ulcers under the metatarsalheads (MTHs). Twenty diabetic patients (3 Type 1 and 17 Type 2) each with 1 plantar ulcer and 23 Type 2 diabetic patients without plantar ulceration (controls), were investigated. The parameters of plantar pressure, length of contact time and pressure-time integral (PTI) were determined by pedography at defined foot regions. PTI represents the duration of mechanical stress on the foot. Based on the distribution of ulcers, the ratio of stress on the MTHs to that on the big toe was calculated. In diabetic patients with ulcers the difference of PTI between MTHs and hallux was higher at 153% and hence 3.2 times greater than the difference in plantar pressure between MTHs and hallux of 47.3%. In the control group the ratio of difference had a factor of 2 only because the corresponding difference in PTI was 85.1% and the difference in plantar pressure was 43.1%. These results may indicate that increased stress at the MTHs is responsible for the occurrence of planar ulcers compared with other regions of the sole. Diabetic patients with elevated PTI ratio are at risk of developing foot ulcers and therefore have to be provided with orthopaedic shoes to prevent foot ulceration.

摘要

足底前足溃疡的主要危险因素是感觉神经病变导致的保护性感觉丧失以及足底机械应力增加。本研究的目的是找到一个比足底压力更好的参数,以解释跖骨头(MTHs)下方足底溃疡的发生情况。对20名糖尿病患者(3名1型和17名2型)进行了研究,每位患者有1个足底溃疡,同时纳入23名无足底溃疡的2型糖尿病患者作为对照。通过足部压力测定法在特定足部区域测定足底压力、接触时间长度和压力-时间积分(PTI)等参数。PTI代表足部承受机械应力的持续时间。根据溃疡分布情况,计算MTHs与大脚趾上的应力比值。在患有溃疡的糖尿病患者中,MTHs与拇趾之间的PTI差异更高,为153%,因此比MTHs与拇趾之间足底压力47.3%的差异大3.2倍。在对照组中,差异比值仅为2倍,因为相应的PTI差异为85.1%,足底压力差异为43.1%。这些结果可能表明,与足底其他区域相比,MTHs处应力增加是导致足底溃疡发生的原因。PTI比值升高的糖尿病患者有发生足部溃疡的风险,因此必须为其提供矫形鞋以预防足部溃疡。

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