Bouchot O, Prunet D, Gaschignard N, Buzelin J M
Clinique Urologique, Centre Hospitalier Universitaire, Nantes, France.
Prog Urol. 1999 Sep;9(4):703-6.
This study evaluated the changes induced by surgical treatment of varicocele on the classical parameter of the sperm count as well as the parameters of Kruger's classification.
Comparative analysis of sperm concentration, mobility and head morphology was performed on the sperm counts obtained before and 6 months after surgery in 159 infertile patients with clinical left varicocele, suspected of being the only aetiological factor for infertility.
Sperm mobility and the percentage of spermatozoa with normal head morphology were significantly increased after treatment. The percentage of spermatozoa with normal morphology was only slightly improved, due to the absence of improvement of flagellar and intermediate segment abnormalities. Fifty-nine term pregnancies were obtained after treatment, corresponding to 41.1% of treated patients.
Treatment of varicocele in infertile patients can improve sperm count and morphology parameters, particularly abnormalities of the head according to Kruger's strict criteria. The number of pregnancies observed argues in favour of the treatment of varicocele, when it constitutes the only aetiological factor for infertility.
本研究评估精索静脉曲张手术治疗对精子计数经典参数以及克鲁格分类参数的影响。
对159例临床诊断为左侧精索静脉曲张且怀疑是不孕唯一病因的不育患者,在手术前和术后6个月获取的精子计数进行精子浓度、活力和头部形态的比较分析。
治疗后精子活力和头部形态正常的精子百分比显著增加。由于鞭毛和中段异常未得到改善,形态正常的精子百分比仅略有提高。治疗后获得了59例足月妊娠,占治疗患者的41.1%。
不育患者的精索静脉曲张治疗可改善精子计数和形态参数,特别是根据克鲁格严格标准的头部异常。当精索静脉曲张是不孕的唯一病因时,观察到的妊娠数量支持对其进行治疗。