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退行性腰椎管狭窄症手术疗效的预测因素

Predictors of surgical outcome in degenerative lumbar spinal stenosis.

作者信息

Katz J N, Stucki G, Lipson S J, Fossel A H, Grobler L J, Weinstein J N

机构信息

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA.

出版信息

Spine (Phila Pa 1976). 1999 Nov 1;24(21):2229-33. doi: 10.1097/00007632-199911010-00010.

Abstract

STUDY DESIGN

A prospective, observational study.

OBJECTIVES

To identify outcome predictors of surgery for degenerative lumbar spinal stenosis.

SUMMARY OF BACKGROUND DATA

Degenerative lumbar spinal stenosis is the most frequent indication for spine surgery in the elderly. More than 25% of surgical patients have a poor outcome, yet little is known about factors that predict the outcome of surgery.

METHODS

Surgery was performed on 199 patients with degenerative lumbar spinal stenosis, and they were observed for 2 years after surgery in four referral centers. Surgery consisted of decompressive laminectomy with or without arthrodesis. Outcomes included validated measures of symptom severity, walking capacity, and satisfaction with the results of surgery. Potential predictors of outcome included sociodemographic factors and physical examination, as well as radiographic, psychological, social, and clinical history variables.

RESULTS

The proportion of patients with severe pain decreased from 81% before surgery to 31% by 2 years afterward. The most powerful preoperation predictor of greater walking capacity, milder symptoms, and greater satisfaction was the patient's report of good or excellent health before surgery. Low cardiovascular comorbidity also predicted a favorable outcome.

CONCLUSIONS

Patient's assessments of their own health and comorbidity are the most cogent outcome predictors of surgery for spinal stenosis.

摘要

研究设计

一项前瞻性观察性研究。

目的

确定退变性腰椎管狭窄症手术的预后预测因素。

背景资料总结

退变性腰椎管狭窄症是老年人脊柱手术最常见的适应证。超过25%的手术患者预后不佳,但对于预测手术预后的因素知之甚少。

方法

对199例退变性腰椎管狭窄症患者进行手术,并在四个转诊中心术后观察2年。手术包括减压性椎板切除术,可伴有或不伴有关节融合术。预后指标包括症状严重程度、步行能力以及对手术结果满意度的有效测量。预后的潜在预测因素包括社会人口统计学因素、体格检查以及影像学、心理、社会和临床病史变量。

结果

严重疼痛患者的比例从术前的81%降至术后2年的31%。术前对步行能力增强、症状较轻和满意度较高最有力的预测因素是患者术前报告健康状况良好或极佳。低心血管合并症也预示着良好的预后。

结论

患者对自身健康和合并症的评估是腰椎管狭窄症手术最有说服力的预后预测因素。

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