Segura Martín M, Lorenzo Romero J G, Salinas Sánchez A A, Hernández Millán I, Cañamares Pabolaza L, Virseda Rodriguez J A
Department of Urology, Complejo Hospitalario de Albacete, Spain.
Urol Int. 1999;62(4):226-8. doi: 10.1159/000030402.
Myelolipomas are rare benign tumors often found incidentally due, in the majority of cases, to the fact that they are asymptomatic. The incidence of adrenal myelolipomas at autopsy is low (0.2%). These tumors are made up of fat and hematopoietic cells. Their origin is unclear and different theories have been put forward, including development from rests of mesenchymal stem cells, embolism of bone marrow, extramedullary hematopoiesis and, according to the most widely accepted theory, metaplasia of the reticuloendothelial cells of blood capillaries. Due to their uncertain etiology and low frequency, management of adrenal myelolipomas is usually individualized and carried out depending on the protocols of each center. The development of improved imaging techniques has increased their diagnosis in routine clinical practice. Thus, they have been included in the heterogeneous group of 'incidentalomas' of the adrenal gland.
肾上腺髓质脂肪瘤是一种罕见的良性肿瘤,多数情况下因其无症状而常被偶然发现。肾上腺髓质脂肪瘤在尸检中的发生率较低(0.2%)。这些肿瘤由脂肪和造血细胞组成。其起源尚不清楚,已提出了不同的理论,包括间充质干细胞残余的发育、骨髓栓塞、髓外造血,以及根据最广泛接受的理论,毛细血管网状内皮细胞的化生。由于其病因不确定且发病率低,肾上腺髓质脂肪瘤的治疗通常是个体化的,并根据每个中心的方案进行。改进的成像技术的发展增加了其在常规临床实践中的诊断率。因此,它们已被纳入肾上腺“偶发瘤”这一异质性组群中。