Bilen N, Apaydin R, Erçin C, Harova G, Başdaş F, Bayramgürler D
Department of Dermatology, Kocaeli University, Faculty of Medicine, Izmit, Turkey.
J Eur Acad Dermatol Venereol. 1999 Sep;13(2):113-7.
A large number of dermatoses associated with either morphea and psoriasis have been reported. However, to the best of our knowledge there is only one report in the literature about coexistence of morphea and psoriasis. Here we report a case of morphea and psoriasis that improved with acitretin treatment. The concomitant occurrence of these two dermatoses may be explained by immunological factors or trauma. We think that the improvement of the morphea lesions may be due to an immunomodulatory effect of the drug or a decrease in collagen production by dermal fibroblasts due to retinoic acid.
已有大量关于与硬斑病和银屑病相关的皮肤病的报道。然而,据我们所知,文献中仅有一篇关于硬斑病和银屑病共存的报道。在此,我们报告一例经阿维A治疗后病情改善的硬斑病和银屑病病例。这两种皮肤病的同时出现可能由免疫因素或创伤所解释。我们认为硬斑病皮损的改善可能是由于药物的免疫调节作用,或者是由于维甲酸导致真皮成纤维细胞产生的胶原蛋白减少。