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[低脑重和高脑重选择的小鼠焦虑水平和应激反应的比较]

[The comparison of levels of anxiety and stress response in mice selected for low and high brain weight].

作者信息

Markina N V, Popova N V, Salimov R M, Salimova N B, Savchuk O V, Poletaeva I I

机构信息

Lomonosov State University, Moscow.

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1999 Sep-Oct;49(5):789-98.

Abstract

Emotionality, anxiety and stress reactivity were studied in mice selected for large (LW) and small (SW) brain weight. The open-field test, startle reaction, cross-maze, tail suspension and slippery funnel tests were used. It was shown that the SW mice are more active in the open field, more anxious and predisposed to the stereotyped behavior and passive reactions in stress situations. The relationship between the studied traits and brain weight and their influence on cognitive behavior are discussed.

摘要

对大脑重量大(LW)和小(SW)的小鼠进行了情绪性、焦虑和应激反应性的研究。采用旷场试验、惊吓反应、十字迷宫试验、悬尾试验和滑漏斗试验。结果表明,SW小鼠在旷场中更活跃,更焦虑,在应激情况下更容易出现刻板行为和被动反应。讨论了所研究的性状与脑重量之间的关系及其对认知行为的影响。

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