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[卡耶塔环孢子虫:一种新出现的肠道病原体综述]

[Cyclospora cayetanensis: review of an emerging intestinal pathogen].

作者信息

Serpentini A, Dutoit E, Camus D

机构信息

Laboratoire de parasitologie et de mycologie, 1, place de Verdun, CHRU, 59045 Lille Cedex.

出版信息

Ann Biol Clin (Paris). 1999 Nov-Dec;57(6):677-83.

Abstract

Cyclospora cayetanensis is an emerging pathogen. It is a new human coccidian agent of intestinal disease. Twenty years ago, the first known human cases of cyclosporiasis were reported in the medical literature. Cyclosporiasis occurs in persons of all ages and either in immunocompetent or immunocompromised hosts. The most characteristic feature of this infection is a syndrome of acute or chronic diarrhea. This parasite has a world-wide distribution. In previous reports, Cyclospora cayetanensis was associated with prolonged diarrhea in travellers, returning from developing countries. However, Cyclospora infection has recently been reported in non travellers in the United States and Canada. Cyclospora can be transmitted by ingestion of water or food contaminated with oocysts. The life cycle of Cyclospora cayetanensis is not fully known. Diagnosis of cyclosporiasis is made by direct examination of stool samples. To date, oral trimethoprim-sulfamethoxazole is the only effective treatment for Cyclospora infection.

摘要

卡耶塔环孢子虫是一种新出现的病原体。它是一种引起肠道疾病的新型人体球虫病原体。20年前,医学文献中首次报道了已知的人类环孢子虫病病例。环孢子虫病可发生于所有年龄段的人群,包括免疫功能正常或免疫功能低下的宿主。这种感染最典型的特征是急性或慢性腹泻综合征。这种寄生虫在全球范围内均有分布。在以往的报告中,卡耶塔环孢子虫与从发展中国家返回的旅行者的长期腹泻有关。然而,最近在美国和加拿大的非旅行者中也报告了环孢子虫感染病例。环孢子虫可通过摄入被卵囊污染的水或食物传播。卡耶塔环孢子虫的生命周期尚未完全明确。环孢子虫病的诊断通过直接检查粪便样本进行。迄今为止,口服甲氧苄啶-磺胺甲恶唑是治疗环孢子虫感染的唯一有效方法。

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