Popovici Irina, Dahorea Cătălina, Rugină Aurica, Coman Gabriela
Disciplina de Microbiologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2003 Oct-Dec;107(4):877-80.
Acute diarrhea is a major problem with high morbidity and mortality rates in developing countries, especially in children. Complex laboratory investigations are required to define the etiology because of the broad spectrum of etiological agents and the non-specific clinical signs. In the last decade, Cyclospora cayetanensis--a new acid-fast coccidian species--was pointed to be the cause of watery self-limited or prolonged diarrhea in immunocompetent and immunocompromised patients, with very good evolution after treatment with co-trimoxazole. Unlike Cryptosporidium parvum, nonsporulated Cyclospora oocysts are eliminated in feces, with no risk of human to human transmission. Cyclospora cayetanensis is widely spread, producing endemic infections, in Asia and South America and was reported to produce infections in foreign travellers in these areas and epidemic outbreaks of foodborne diarrhea. We describe the first case of acute diarrhea associated with Cyclospora cayetanensis in an immunocompetent child admitted to Iaşi "Sf. Maria" Hospital.
急性腹泻在发展中国家是一个主要问题，发病率和死亡率都很高，尤其是在儿童中。由于病原体种类繁多且临床症状不具特异性，因此需要进行复杂的实验室检查来确定病因。在过去十年中，卡耶塔环孢子球虫——一种新的抗酸球虫种类——被认为是免疫功能正常和免疫功能低下患者中水样自限性或持续性腹泻的病因，用复方新诺明治疗后恢复良好。与微小隐孢子虫不同，未孢子化的环孢子虫卵囊会随粪便排出，不存在人传人的风险。卡耶塔环孢子球虫广泛传播，在亚洲和南美洲引发地方性感染，据报道在这些地区感染外国旅行者，并引发食源性腹泻的疫情爆发。我们描述了首例在雅西“圣玛丽亚”医院收治的免疫功能正常儿童中与卡耶塔环孢子球虫相关的急性腹泻病例。
