5型腺病毒DNA的复制机制。
The mechanism of replication of adenovirus type 5 DNA.
作者信息
Sussenbach J S, Ellens D J, Van Der Vliet P C, Kuijk M G, Steenbergh P H, Vlak J M, Rozijn T H, Jansz H S
出版信息
Cold Spring Harb Symp Quant Biol. 1975;39 Pt 1:539-45. doi: 10.1101/sqb.1974.039.01.066.
The analysis of replicating Ad5 DNA has led to a model for replication involving linear intermediates. The origin of replication has been localized at the molecular right end, suggesting the presence of a unique sequence of nucleotides which can be recognized by an initiation factor. On the other hand, the study of the molecular ends has shown, so far, a high degree of symmetry in the terminal nucleotide sequences of Ad5 DNA. A more detailed study of the nucleotide sequences at the ends is necessary to solve this problem.
对腺病毒5型（Ad5）复制型DNA的分析得出了一个涉及线性中间体的复制模型。复制起点已定位在分子右端，这表明存在一段独特的核苷酸序列，可被起始因子识别。另一方面，迄今为止对分子末端的研究表明，Ad5 DNA末端核苷酸序列具有高度对称性。为解决这个问题，有必要对末端的核苷酸序列进行更详细的研究。
Zotero 插件