Jurkiewicz D, Wolska K I
Department of Bacterial Genetics, University of Warsaw, Poland.
Acta Microbiol Pol. 1999;48(2):197-201.
E. coli defects in response to nutritional starvation caused by DnaK and DnaJ proteins deprivation are examined. The ability of delta dnaKdnaJ mutant to survive carbon, nitrogen and phosphorus starvation is highly impaired while delta dnaJ mutant is characterized by the diminished survival of phosphorus starvation only. delta dnaKdnaJ mutant grows slowly utilizing maltose and glycerol and delta dnaJ mutant utilizes glycerol inefficiently. The growth on alternate nitrogen sources is comparable to wild-type strain.
研究了大肠杆菌因缺乏DnaK和DnaJ蛋白而对营养饥饿产生的反应缺陷。ΔdnaKdnaJ突变体在碳、氮和磷饥饿条件下的存活能力严重受损，而ΔdnaJ突变体仅表现为在磷饥饿条件下存活率降低。ΔdnaKdnaJ突变体利用麦芽糖和甘油生长缓慢，而ΔdnaJ突变体利用甘油的效率低下。在替代氮源上的生长与野生型菌株相当。
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