[三甲氧苯乙胺和麦角酰二乙胺对大鼠离体器官对儿茶酚胺的机械反应的影响以及钙转运在这些现象中的作用]
[Effects of mescaline and lysergide on the mechanical responses of isolated organs of the rat to catecholamines and the role of calcium transfers in these phenomena].
作者信息
Valette G, Leclair M F
出版信息
C R Acad Hebd Seances Acad Sci D. 1978 Oct 30;287(11):1055-8.
PMID:105820
Abstract
On isolated Rat vas deferens the contracting responses of noradrenaline and dopamine are increased by mescaline (23 micromoles) and decreased by lysergide (15 micromoles). Similarly, on isolated Rat duodenum previously decalcified the hypertonic responses of recalcification are modified in the opposite direction by the two agonists. On the other hand, mescaline such as lysergide increase the fall of tonus which ensues the decalcification of isolated duodenum.
摘要
在离体大鼠输精管上，麦司卡林（23微摩尔）可增强去甲肾上腺素和多巴胺的收缩反应，而麦角酰二乙胺（15微摩尔）则使其减弱。同样，在预先脱钙的离体大鼠十二指肠上，这两种激动剂对再钙化的高渗反应产生相反方向的改变。另一方面，麦司卡林和麦角酰二乙胺一样，会增强离体十二指肠脱钙后随之出现的张力下降。
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