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[伊波加（Tabernanthe iboga H. Bn.）生物碱对离体器官对儿茶酚胺反应的影响及钙交换的可能作用。以伊波加因为例]

[The effect of alkaloids from Tabernanthe iboga H. Bn. on the response of isolated organs to catecholamines and the possible role of calcium exchange. Case of Ibogaine].

作者信息

Valette G, Leclair M F

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Oct 31;285(11):1147-50.

PMID:413652
Abstract

On isolated Rat duodenum, ibogaine (70 mumoles/l) increases the hypertonic effect following the addition of Calcium ions to the organ previously decalcified. Moreover, this alkaloid increases the hypotomic effect resulting from decalcification of the normal organs. These actions are taken into account with the potentiating effects of ibogaine on noradrenaline and dopamine responses observed on rat vas deferens.

摘要

在离体大鼠十二指肠上，伊波加因（70微摩尔/升）在向先前已脱钙的器官中添加钙离子后会增强高渗效应。此外，这种生物碱会增强正常器官脱钙所产生的低渗效应。这些作用与伊波加因对大鼠输精管上观察到的去甲肾上腺素和多巴胺反应的增强作用一并考虑。

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1
[The effect of alkaloids from Tabernanthe iboga H. Bn. on the response of isolated organs to catecholamines and the possible role of calcium exchange. Case of Ibogaine].[伊波加（Tabernanthe iboga H. Bn.）生物碱对离体器官对儿茶酚胺反应的影响及钙交换的可能作用。以伊波加因为例]
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引用本文的文献

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Ibogaine modulates cocaine responses which are altered due to environmental habituation: in vivo microvoltammetric and behavioral studies.伊波加因可调节因环境适应而改变的可卡因反应：体内微伏安法和行为学研究。
Pharmacol Biochem Behav. 1994 Nov;49(3):711-28. doi: 10.1016/0091-3057(94)90092-2.